Cell cycle regulation and hematologic malignancies
نویسندگان
چکیده
منابع مشابه
Targeting cell cycle regulators in hematologic malignancies
Hematologic malignancies represent the fourth most frequently diagnosed cancer in economically developed countries. In hematologic malignancies normal hematopoiesis is interrupted by uncontrolled growth of a genetically altered stem or progenitor cell (HSPC) that maintains its ability of self-renewal. Cyclin-dependent kinases (CDKs) not only regulate the mammalian cell cycle, but also influence...
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ژورنال
عنوان ژورنال: Blood Science
سال: 2019
ISSN: 2543-6368,2543-6368
DOI: 10.1097/bs9.0000000000000009